Phorbol myristoyl acetate
WebMay 1, 2024 · Abstract Introduction: THP-1 cells, a human leukemia monocytic cell line, differentiated by phorbol myristate acetate (PMA) are widely used as surrogate of human … WebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a phorbol ester and PKC activator. 1, 2, 3, 4, 5 It activates the PKC isoforms PKCα, -β, -γ, -δ, -ε, -η, and -θ but not PKCζ or -ι/λ. 2 PMA (1-10 ng/ml) induces NF-κB-dependent gene expression in a reporter assay. 3 It promotes the differentiation …
Phorbol myristoyl acetate
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WebCD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [4]. On 3, NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of mAb. In addition to activated immune effectors, 4-1BB is also expressed on innate immune cell populations, including WebIn order to test the biological relevance and potential interaction of MLK 3 with protein kinase C-mediated signaling pathways, human MLK 3 was stably expressed in rat glomerular mesangial cells using a retroviral vector (LXSN) and the effects of phorbol myristoyl acetate (PMA) on DNA synthesis and osteopontin mRNA expression were examined.
Webdisulfonic acid, phorbol myristoyl acetate (PMA), desferrioxamine, and all other reagents were from Sigma. 55FeCl 3 (9.1 mM, 20 mCi/mg) was from PerkinElmer Life Sciences. A 55Fe-NTA solution was prepared by incubating 55FeCl 3 (9.1 mM) and NTA (45.5 mM) for 1 h. The resulting 55Fe-NTA solution was mixed at a 1:9 molar ratio with unlabeled WebMar 31, 2016 · Some of the canonic immunostimulatory agents known to induce 4-1BB upregulation on T cells include: Con A, plate-bound anti-CD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [3, 4]. On NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of …
WebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). PMA activates PKC isoforms through the binding of the C1 domain (Hurley et al.). PMA … Web3株钩体均在EMJH培养基中置28 ℃需氧培养至对数期备用。佛波酯(phorbol myristoyl acetate, PMA)购自Sigma公司，SYBR®PrimeScriptTMRT-PCR Kit购自大连TaKaRa公司，人细胞因子ELISA试剂盒购自R&D公司，ABI 7500 Fast为美国应用生物系统公司产品。 ...
WebPhorbol myristate acetate (PMA; phorbol ester) activates protein kinase C, which then activates a wide range of signaling pathways, including ERK via effects on the upstream …
WebSAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 24-Dec-2024 Revision Number 4 1. Identification Product Name Phorbol 12-myristate 13-acetate Cat No. : BP685, BP685-1, BP685-10, BP685-5 CAS No 16561-29-8 Synonyms PMA Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product use. … ct with contrast for bleedWebMar 31, 2024 · Definition. A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. Structure. Top Interacting. Genes. 0 50 100 150 200 250 MMP9 PTGS2 IL2 MAPK3 MAPK1 TNF IL6 JUN RELA CXCL8 Interactions. Actor name. Interactions with Tetradecanoylphorbol Acetate. easiest way to get out of s modeWebIn order to test the biological relevance and potential interaction of MLK 3 with protein kinase C-mediated signaling pathways, human MLK 3 was stably expressed in rat glomerular mesangial cells using a retroviral vector (LXSN) and the effects of phorbol myristoyl acetate (PMA) on DNA synthesis and osteopontin mRNA expression were examined. easiest way to get photos off iphoneWebMay 3, 2013 · Overview Product name Phorbol 12-myristate 13-acetate (PMA), PKC activator Description PKC activator Alternative names PMA CAS Number 16561-29-8 Chemical structure Properties Associated products Applications Images Protocols Datasheets and documents References (31) Customer reviews and Q&As ct with contrast costWebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a specific activator of Protein Kinase C (PKC) and hence activates … ct with contrast for lung noduleWebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. … ct with contrast definitionWebPhorbol myristate acetate treatment of normal human myeloid blast cells promotes monopoiesis and inhibits granulopoiesis Leuk Res. 1990;14(11-12):1007-17. doi: … ct with contrast for staging