WebNov 18, 2016 · Tendon disease is characterized by the development of fibrosis. Transforming growth factor beta (TGF-β), bone morphogenic proteins (BMPs) and connective tissue growth factor (CTGF) are key mediators in the pathogenesis of fibrotic disorders. The aim of this systematic review was to investigate the evidence for the … WebObjectives: To clarify the role of cellular communication network factor 2/connective tissue growth factor (CCN2/CTGF) in periodontal tissue regeneration by investigating, the proliferative and tubulogenic responses of human endothelial cells obtained from the periodontal ligament to CCN2/CTGF.
CTGF is a central mediator of tissue remodeling and …
WebJun 6, 2012 · CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, … WebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} … poor harry\u0027s bar penn hills pa
Connective tissue growth factor promotes cell‐to‐cell communication …
WebSep 1, 2024 · Connective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on … WebConnective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on heparan sulfate. ... At 10 weeks, surgical destabilisation of the joint, by cutting the … WebOct 5, 2005 · Connective tissue growth factor (CCN2/CTGF) is a cysteine-rich protein with a molecular weight of 36–38 kDa [1–3] and belongs to the CCN family, which stands for C … poor harry 意味